Max Verstappen claims dramatic Brazilian Grand Prix win from 17th to close in on title
McLaren's Norris, who started the wet and chaotic Sao Paulo race on pole position and 44 points behind Verstappen, finished sixth and under investigation for a procedural infringement at the initial aborted start.
The title gap meanwhile blew out to 62 points, possibly more if the stewards penalise the Briton, with three rounds remaining.
If results go his way, Verstappen could hit the jackpot in the next race in Las Vegas on November 23rd.
In a crash-strewn race halted after 33 laps and re-started, Verstappen took his eighth win of the season by a mighty 19.477 seconds and with a bonus point for the fastest lap.
"We stayed out of trouble, we made the right calls and stayed calm and we were flying so all of these things together made that result possible," said Verstappen.
"But I mean unbelievable, to win here from so far back on the grid."
With team boss Christian Horner acclaiming a masterclass of a drive from one of the sport's greats, the win ended a 10-race losing streak for the 27-year-old Dutch driver dating back to Spain in June.
Astonishing Alpine
Amid the mayhem at Interlagos, Alpine took an astonishing points bonanza with Esteban Ocon second and Pierre Gasly third -- rocketing the Renault-owned team from ninth to sixth in the standings.
"I don’t think anyone would have got that on their bingo card, it’s just fantastic," said Gasly.
George Russell finished fourth for Mercedes with Ferrari's Charles Leclerc fifth.
Yuki Tsunoda was seventh for RB with McLaren's Oscar Piastri eighth, Liam Lawson ninth for RB and Mercedes's seven-times champion Lewis Hamilton 10th.
Verstappen now has 393 points to Norris's 331, with Leclerc on 307.
McLaren lead the constructors' standings with 593 points to Ferrari's 557, although that could change if Norris gets a penalty.
"It was a tough day, I did my best. I've had a lot of good races, it was about time that something didn't go right," said Norris, who won the Saturday sprint.
Early call
The day started early, with qualifying held at 0730 local after rain forced a postponement on Saturday.
Verstappen was caught out by red flags in that session, his 12th place on the grid becoming 17th after an engine penalty was applied.
The first race start was aborted when Aston Martin's Lance Stroll went off on the formation lap in treacherous conditions, with Norris leading some of the cars -- but not Verstappen -- away for a second attempt.
He did so before the overhead lights had changed to signal permission to move, however, and stewards were immediately on his case.
With only two cars behind him on the grid, and Ferrari's Carlos Sainz starting from the pitlane, Verstappen scythed through the field in changing conditions and was 10th after two laps while Norris lost out to Russell at the start.
The virtual safety car was deployed on lap 28, after Haas's Nico Hulkenberg had spun off, with Russell and Norris pitting in increasing rain and what turned out to be an unfortunate call as Verstappen, Ocon and Gasly stayed out.
The full safety car was then deployed before Argentine rookie Franco Colapinto crashed his Williams shortly after pitting, scattering debris across the track and halting the race.
Colapinto was the sole Williams on track after Alex Albon crashed in qualifying and the team were unable to repair his car in time.
After a 25-minute delay, Ocon led a rolling re-start to the race and Verstappen then took the lead on lap 43, three laps after Sainz crashed at turn eight and triggered another safety car period.
Hulkenberg was excluded for receiving assistance from marshals after spinning off and beaching his car on a drain on lap 27.